BACE1 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Synonyms
ASP2; BACE; HSPC104; Beta-secretase 1; Aspartyl protease 2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2; BACE1; KIAA1149
Gene ID
23621
Swiss Prot
P56817
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
401-501/501
Target
BACE1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human BACE1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23621
Predicted Cross Reactivity
Dog, Pig, Chicken, Rabbit, GuineaPig
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx525301 96 Tests
Human GTPase IMAP family member 6 (GIMAP6) ELISA Kit
Sign In for Pricing
View Details 
LV761935 1.0 µg DNA
GAPDHP39 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
Sign In for Pricing
View Details AMM19526V 100 µL
AEBP2 Mouse Monoclonal Antibody [Clone ID: LBI10F3]
Sign In for Pricing
View Details 
MBS7202915-01 48 Well
Monkey Chorion-specific transcription factor GCMa (GCM1) ELISA Kit
Sign In for Pricing
View Details