GTP cyclohydrolase 1 Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Synonyms
GTP-CH-1; DYT 5; DYT5; GCH 1; GCH; GCH1; GTP CH 1; GTP CH I; GTP cyclohydrolase 1 dopa responsive dystonia; GTP cyclohydrolase 1; GTP cyclohydrolase I; GTPCH 1; GTPCH1; Guanosine 5' triphosphate cyclohydrolase I.
Gene ID
2643
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
34-110/250
Target
GTP cyclohydrolase 1
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human GTP-CH-1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2643
Predicted Cross Reactivity
Human, Rat
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15287001 1 Vial
Lentiviral mouse Dthd1 shRNA (UAS) - Lentiviral mouse Dthd1 shRNA (UAS, GFP) (100)
Ask
View Details 
MBS1038234-01 0.02 mg (E-Coli)
Recombinant Influenza A virus Non-structural protein 1 (NS)
Ask
View Details MBS1038234-02 0.1 mg (E-Coli)
Recombinant Influenza A virus Non-structural protein 1 (NS)
Ask
View Details