Leptin Receptor Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Receptor for obesity factor (leptin) . On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity) .

Synonyms

OBR; OB-R; CD295; LEP-R; LEPRD; Leptin receptor; HuB219; OB receptor; LEPR; DB; LEPR_MOUSE

Gene ID

3953

Swiss Prot

P48357

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

901-1000/1165

Target

Leptin receptor (Isoform B)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody will recognize the Isoform B variant only

Gene ID URL

3953

Predicted Cross Reactivity

Dog, Cow, Sheep, Pig

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