Caspase-10 Polyclonal Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.
Synonyms
MCH4; ALPS2; FLICE2; Caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; ICE-like apoptotic protease 4; CASP10
Gene ID
843
Swiss Prot
Q92851
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Immunogen
431-521/521
Target
Caspase-10
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human Caspase-10
Applications
FCM
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
1µg/µl
Dilution
FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
843
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
043472-ML405 100 µL
TUSC5, ID (TUSC5, IFITMD3, LOST1, Tumor suppressor candidate 5, Dispanin subfamily B member 1, Interferon-induced transmembrane domain-containing protein D3, Protein located at seventeen-p-thirteen point three 1) (MaxLight 405) discontinued
Ask
View Details 
MBS6009379-01 0.1 mg
TRIM35 (Tripartite Motif Containing 35, Tripartite Motif-containing 35, KIAA1098, Hemopoietic lineage switch protein 5, HLS5)
Ask
View Details MBS6009379-02 5x 0.1 mg
TRIM35 (Tripartite Motif Containing 35, Tripartite Motif-containing 35, KIAA1098, Hemopoietic lineage switch protein 5, HLS5)
Ask
View Details 