IDE Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Synonyms
INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE
Gene ID
3416
Swiss Prot
P14735
Cellular Locus
Cytoplasm, Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
491-590/1019
Target
IDE
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from human IDE
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3416
Predicted Cross Reactivity
Human, Cow, Pig, Chicken
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