IGF 1 Polyclonal Antibody

Product Specifications

Background

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.

Synonyms

IGFI; IGF-I; IGF1A; Insulin-like growth factor I; Mechano growth factor; MGF; Somatomedin-C; IGF1; IBP1

Gene ID

3479

Swiss Prot

P05019

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Dog

Immunogen

49-100/195

Target

IGF 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human IGF-1

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC), IP

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200), IP (1-2ug)