CD40L Recombinant Antibody
Product Specifications
Background
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Synonyms
CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40LG; CD40L; TNFSF5; TRAP.
Gene ID
959
Swiss Prot
P29965
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
CD40L
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CD40L
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at 4°C for short term. Store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Gene ID URL
959
Isotype
IgG
Curated Selection
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