Thioredoxin Recombinant Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.

Synonyms

TXN; ADF; ATL-derived factor; SASP; Thioredoxin; TRX1; Thioredoxin delta 3; TRX; TXN delta 3; TRDX.

Gene ID

7295

Swiss Prot

P10599

Cellular Locus

Cytoplasm, Nucleus, Secreted

Host

Rabbit

Cross Reactivity

Human

Target

Thioredoxin

Clonality

Recombinant

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human Thioredoxin

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7295

Isotype

IgG

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