TBX21 Recombinant Antibody
Product Specifications
Background
Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs.Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Induces permissive chromatin accessibilty and CpG methylation in IFNG.
Synonyms
T bet; T box 21; T PET; TBET; TBLYM; Tbx21; TPET; Transcription factor TBLYM.
Gene ID
30009
Swiss Prot
Q9UL17
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
Tbx21
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TBX21
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
30009
Isotype
IgG
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