Phospho-SMC1 alpha (Ser957) Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.

Synonyms

SB1.8/DXS423E protein; SM1A; SMC1A; SMC1L1; SMC1alpha protein; Sb1.8

Gene ID

8243

Swiss Prot

Q14683

Modification Site

Ser957

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

SMC1 alpha

Clonality

Recombinant

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human SMC1 alpha around the phosphorylation site of S957

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8243

Isotype

IgG

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