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PKC delta/theta Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Calcium-independent, phospholipid- and diacylglycerol (DAG) -dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.

Synonyms

ALPS3; CVID9; MAY1; nPKC-delta; nPKC-theta; PKCD; PRKCD; PRKCQ; PRKCT; Protein kinase C delta type; Protein kinase C theta type; SDK1; Sphingosine-dependent protein kinase-1; Tyrosine-protein kinase PRKCD.

Gene ID

5580

Swiss Prot

Q05655, Q04759, P28867

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PKC delta/theta

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human PKC delta

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5580

Isotype

IgG

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