PKC delta/theta Recombinant Antibody
Product Specifications
Background
Calcium-independent, phospholipid- and diacylglycerol (DAG) -dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.
Synonyms
ALPS3; CVID9; MAY1; nPKC-delta; nPKC-theta; PKCD; PRKCD; PRKCQ; PRKCT; Protein kinase C delta type; Protein kinase C theta type; SDK1; Sphingosine-dependent protein kinase-1; Tyrosine-protein kinase PRKCD.
Gene ID
5580
Swiss Prot
Q05655, Q04759, P28867
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
PKC delta/theta
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PKC delta
Applications
WB, IHC-P, IHC-F, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5580
Isotype
IgG
Curated Selection
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