Phospho-LRP6 (Ser1490) Recombinant Antibody
Product Specifications
Background
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.
Synonyms
Low-density lipoprotein receptor-related protein 7.
Gene ID
4040
Swiss Prot
O75581
Modification Site
Ser1490
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
LRP6
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Phosphorylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4040
Isotype
IgG
Curated Selection
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