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PICALM Recombinant Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly.

Synonyms

CALM; CLTH; LAP; PICALM.

Gene ID

8301

Swiss Prot

Q13492

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

PICALM

Clonality

Recombinant

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human PICALM

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8301

Isotype

IgG

Curated Selection

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