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Phospho-Syk (Tyr323) Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR) . Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development.Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains.

Synonyms

KSYK; p72syk; Spleen tyrosine kinase; Syk.

Gene ID

6850

Swiss Prot

P43405

Modification Site

Tyr323

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

Syk

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Syk around the phosphorylation site of Y323

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

6850

Isotype

IgG

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