Phospho-SHIP1 (Tyr1022) Recombinant Antibody
Product Specifications
Background
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns (3,4,5) P3) to produce PtdIns (3,4) P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways.
Synonyms
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SHIP-1; p150Ship; hp51CN; INPP5D; SHIP.
Gene ID
3635
Swiss Prot
Q92835
Modification Site
Tyr1022
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
SHIP1
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human INPP5D around the phosphorylation site of Y1022
Applications
WB, IP, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IP (1-2ug), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Phosphorylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3635
Isotype
IgG
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