HTRA1 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.
Synonyms
ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; IGFBP5 protease; ORF480; Protease serine 11 (IGF binding) ; protease serine 11; PRSS11; Serine protease 11; Serine protease HTRA1.
Gene ID
5654
Swiss Prot
Q92743
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Target
HTRA1
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Serine protease HTRA1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5654
Isotype
IgG
Curated Selection
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