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HTRA1 Recombinant Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.

Synonyms

ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; IGFBP5 protease; ORF480; Protease serine 11 (IGF binding) ; protease serine 11; PRSS11; Serine protease 11; Serine protease HTRA1.

Gene ID

5654

Swiss Prot

Q92743

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human

Target

HTRA1

Clonality

Recombinant

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human Serine protease HTRA1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5654

Isotype

IgG

Curated Selection

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