ICOS ligand Recombinant Antibody, APC Conjugated
Product Specifications
Background
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Synonyms
B7H2; B7RP1; CD275; GL50; ICOSL; Icoslg; LICOS.
Gene ID
23308
Swiss Prot
O75144
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
ICOS ligand
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human ICOS ligand
Applications
WB
Purification
Purified Polyclonal A
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23308
Isotype
IgG
Curated Selection
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