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ICOS ligand Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

Synonyms

B7H2; B7RP1; CD275; GL50; ICOSL; Icoslg; LICOS.

Gene ID

23308

Swiss Prot

O75144

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

ICOS ligand

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human ICOS ligand

Applications

WB

Purification

Purified Polyclonal A

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23308

Isotype

IgG

Curated Selection

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