Phospho-Rb2 p130 (T986) Recombinant Antibody
Product Specifications
Background
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.
Synonyms
130 kDa retinoblastoma associated protein; IB4; p130; PRB2; Rb2; Rbl2; RBR2; Retinoblastoma like 2; Retinoblastoma-related protein 2; RIC128.
Gene ID
5934
Swiss Prot
Q08999
Modification Site
Thr986
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Rb2 p130
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human RBL2 around the phosphorylation site of T986
Applications
WB, IP
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IP (1-2ug)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Phosphorylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5934
Isotype
IgG
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