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GLCNE Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.

Synonyms

DMRV; GNE; IBM2; ManAc kinase; Uae1; GLCNE.

Gene ID

10020

Swiss Prot

Q9Y223

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

GLCNE

Clonality

Recombinant

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human GNE

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10020

Isotype

IgG

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