N6- (4-Hydroxybenzyl) adenosine

N6- (4-Hydroxybenzyl) adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM) . IC50 value: 6.77-141 μM Target: P2Y12receptor Anti-aggregation activity of N6- (4-Hydroxybenzyl) adenosine could involve an interaction with the P2Y12receptor binding site.

Product Specifications

CAS Number

[110505-75-4]

Product Name Alternative

Para-topolin riboside

UNSPSC

12352005

Target

P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/N6-_4-Hydroxybenzyl_adenosine.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)

Smiles

OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NCC4=CC=C(O)C=C4)O1)O)O

Molecular Formula

C17H19N5O5

Molecular Weight

373.36

References & Citations

[1]Vistoli G, et al. Naturally occurring N (6) -substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y (12) receptor. Bioorg Med Chem Lett. 2014 Dec 15;24 (24) :5652-5655.