AKAP95 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) . Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring.
Synonyms
Akap8; AKAP95.
Gene ID
10270
Swiss Prot
O43823
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
AKAP95
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human AKAP 8
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10270
Isotype
IgG
Curated Selection
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