Nck beta Recombinant Antibody, APC Conjugated
Product Specifications
Background
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
Synonyms
GRB4; NCK adaptor protein 2; NCK2; NCKbeta.
Gene ID
8440
Swiss Prot
O43639
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Nck beta
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human NCK2
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8440
Isotype
IgG
Curated Selection
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