Nck beta Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
Synonyms
GRB4; NCK adaptor protein 2; NCK2; NCKbeta.
Gene ID
8440
Swiss Prot
O43639
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Nck beta
Clonality
Recombinant
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human NCK2
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8440
Isotype
IgG
Curated Selection
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