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ABRAXAS1 Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.

Synonyms

ABRA1; ABRAXAS; FAM175A.

Gene ID

84142

Swiss Prot

Q6UWZ7

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

ABRAXAS1

Clonality

Recombinant

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human ABRAXAS1

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

84142

Isotype

IgG

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