ABRAXAS1 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.
Synonyms
ABRA1; ABRAXAS; FAM175A.
Gene ID
84142
Swiss Prot
Q6UWZ7
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
ABRAXAS1
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human ABRAXAS1
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
84142
Isotype
IgG
Curated Selection
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