ABRAXAS1 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.

Synonyms

ABRA1; ABRAXAS; FAM175A.

Gene ID

84142

Swiss Prot

Q6UWZ7

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

ABRAXAS1

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human ABRAXAS1

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

84142

Isotype

IgG

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