Phosphoribosyl pyrophosphate (pentasodium)

Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP[1].

Product Specifications

CAS Number

[108321-05-7]

Product Name Alternative

PRPP (pentasodium)

UNSPSC

12352005

Hazard Statement

H371

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/phosphoribosyl-pyrophosphate-pentasodium.html

Purity

99.42

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(O[Na])(O[Na])=O)O[C@@H]1OP(OP(O[Na])(O[Na])=O)(O[Na])=O

Molecular Formula

C5H8Na5O14P3

Molecular Weight

499.98

Precautions

H371

References & Citations

[1]Schneiter R, et al. The importance of the five phosphoribosyl-pyrophosphate synthetase (Prs) gene products of Saccharomyces cerevisiae in the maintenance of cell integrity and the subcellular localization of Prs1p. Microbiology (Reading) . 2000;146 Pt 12:3269-3278. |[2]Greene ML, et al. Substrate stabilization: genetically controlled reciprocal relationship of two human enzymes. Science. 1970;167 (3919) :887-889.