P73 Recombinant Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. Is an activator of FOXJ1 expression. It is an essential factor for the positive regulation of lung ciliated cell differentiation.

Synonyms

P53-like transcription factor; p53-related protein; P73 alpha protein; p73-alpha; TP73; TRP73; Tumor protein p73.

Gene ID

7161

Swiss Prot

O15350

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

P73

Clonality

Recombinant

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human p73

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7161

Isotype

IgG

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