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THEMIS Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.

Synonyms

Protein THEMIS; SPOT; THEMIS; TSEPA.

Gene ID

387357

Swiss Prot

Q8N1K5

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

THEMIS

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human THEMIS

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

387357

Isotype

IgG

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