NPC1 Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.
Synonyms
Niemann Pick C1 protein precursor; NPC; NPC1.
Gene ID
4864
Swiss Prot
O15118
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
NPC1
Clonality
Recombinant
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human Niemann pick C1
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4864
Isotype
IgG
Curated Selection
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