Mono/Di/TriMethyl-Histone H3.1 (Lys15) Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
H3 histone; HIST1H3A; Histone cluster 1, H3a; H3/l; HIST3H3; H3K14me1; H3K14me2; H3K14me3.
Gene ID
8350
Swiss Prot
P68431
Modification Site
Lys15
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Histone H3.1
Clonality
Recombinant
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Histone H3.1 around the methylation site of K15
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Methylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8350
Isotype
IgG
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