Mono/Di/TriMethyl-Histone H3.1 (Lys15) Recombinant Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
H3 histone; HIST1H3A; Histone cluster 1, H3a; H3/l; HIST3H3; H3K14me1; H3K14me2; H3K14me3.
Gene ID
8350
Swiss Prot
P68431
Modification Site
Lys15
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Histone H3.1
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Histone H3.1 around the methylation site of K15
Applications
WB, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Methylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8350
Isotype
IgG
Curated Selection
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