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Crotonyl-Histone H2B type 2E (Lys12) Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone H2B type 1-H; Histone H2B.j; H2B/j; HIST1H2BH; H2BFJ.

Gene ID

8349

Swiss Prot

Q16778

Modification Site

Lys12

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Crotonyl-Histone H2B type 2E (Lys12)

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the crotonylation site of K12

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Crotonylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8349

Isotype

IgG

Curated Selection

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