Crotonyl-Histone H2B type 2E (Lys12) Recombinant Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Histone H2B type 1-H; Histone H2B.j; H2B/j; HIST1H2BH; H2BFJ.
Gene ID
8349
Swiss Prot
Q16778
Modification Site
Lys12
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Crotonyl-Histone H2B type 2E (Lys12)
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the crotonylation site of K12
Applications
WB, IHC-P, IHC-F, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Crotonylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8349
Isotype
IgG
Curated Selection
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