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(R) -HTS-3 (GLXC-25878)

Selected Variant

E1536-01

Size: 5 mg

(R) -HTS-3 (GLXC-25878) is a potent, selective, and cell-active inhibitor of lysophosphatidylcholine acyltransferase 3 (LPCAT3) with an IC50 of 0.09 μM, an enzyme critical for synthesizing C20:4-containing phospholipids. It reduces arachidonic acid-d8 incorporation into phospholipids and mitigates RSL3-induced ferroptosis in HT-1080 and 786-O cancer cells.

Product Specifications

CAS Number

2771208-83-2

Synonyms

GLXC-25878

Target

Others

Activity

Others

Molecular Formula

C17H18F2N2O

Storage Conditions

2 years -20°C liquid

Available Sizes

Price

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