ABI2 Recombinant Antibody, PE Conjugated
Product Specifications
Background
Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation.Acts as a regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge.
Synonyms
Abelson interactor 2; ABI2; ABI2B; Abl binding protein 3; AblBP3; ArgBP1; ARGBPIA; ArgBPIB; SSH3BP2.
Gene ID
10152
Swiss Prot
Q9NYB9
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
ABI2
Clonality
Recombinant
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human ABI2
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10152
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC402677 20 µg
YANK2 (STK32B) (NM_018401) Human Over-expression Lysate
Sign In for Pricing
View Details 
LY427711 100 µg
Synaptotagmin 1 (SYT1) (NM_001135806) Human Over-expression Lysate
Sign In for Pricing
View Details 
TP304379L 1 mg
ZNF385 (ZNF385A) (NM_015481) Human Recombinant Protein
Sign In for Pricing
View Details 