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DOCK2 Recombinant Antibody

Product Specifications

Background

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Synonyms

DOCK 2; IMD40.

Gene ID

1794

Swiss Prot

Q92608

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

DOCK2

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Dedicator of cytokinesis protein 2

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

1794

Isotype

IgG

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