RYK Recombinant Antibody, HRP Conjugated
Product Specifications
Background
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Synonyms
ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik.
Gene ID
6259
Swiss Prot
P34925
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
RYK
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human RYK
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6259
Isotype
IgG
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