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RYK Recombinant Antibody

Product Specifications

Background

May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Synonyms

ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik.

Gene ID

6259

Swiss Prot

P34925

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

RYK

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human RYK

Applications

WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6259

Isotype

IgG

Curated Selection

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