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G3BP1 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Protein involved in various processes, such as stress granule formation and innate immunity.Plays an essential role in stress granule formation.Stress granules are membraneless compartments that store mRNAs and proteins, such as stalled translation pre-initiation complexes, in response to stress.Promotes formation of stress granules phase-separated membraneless compartment by undergoing liquid-liquid phase separation (LLPS) upon unfolded RNA-binding: functions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular free RNA concentrations.

Synonyms

G3BP; G3bp1; hDH VIII.

Gene ID

10146

Swiss Prot

Q13283

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

G3BP1

Clonality

Recombinant

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human G3BP1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10146

Isotype

IgG

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