RING1 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
Synonyms
Ring1A; Ring1; RING1A; Rnf1.
Gene ID
6015
Swiss Prot
Q06587
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
RING1
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human RING1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6015
Isotype
IgG
Curated Selection
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