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RING1 Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

Synonyms

Ring1A; Ring1; RING1A; Rnf1.

Gene ID

6015

Swiss Prot

Q06587

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

RING1

Clonality

Recombinant

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human RING1

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6015

Isotype

IgG

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