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Anti-CD11a [hu1124 (Efalizumab) ]

Human monoclonal antibody to CD11a

Product Specifications

Product Name Alternative

LFA-1; integrin alpha L

UniProt

P20701

Reactivity

Human

Immunogen

Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.

Target

CD11a

Clonality

Monoclonal

Clone

Hu1124 (Efalizumab)

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Concentration

1 mg/ml

Purity

Purified

References & Citations

Bauer, R. J. et al. Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis J Pharmacokinet Biopharm, 27, 397-420 (1999)

Pubmed id

10826130

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

Blocking, FC

Host or Source

Human

Preservative

PBS with 0.02% Proclin 300.

Isotype

IgG1

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