Anti-CD22 [hL22 (Epratuzumab) ]
Human monoclonal antibody to CD22
Product Specifications
Product Name Alternative
Leu14; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14
UniProt
P20273
Reactivity
Human, Primate
Immunogen
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5–10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010) .
Target
CD22
Clonality
Monoclonal
Clone
HL22 (Epratuzumab)
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
1 mg/ml
Purity
Purified
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
Blocking, FC, IP
Host or Source
Human
Preservative
PBS with 0.02% Proclin 300.
Isotype
IgG1
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