TREX1 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements.
Synonyms
AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1.
Gene ID
11277
Swiss Prot
Q9NSU2
Host
Rabbit
Cross Reactivity
Human
Target
TREX1
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human TREX1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
11277
Isotype
IgG
Curated Selection
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