TREX1 Recombinant Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements.

Synonyms

AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1.

Gene ID

11277

Swiss Prot

Q9NSU2

Host

Rabbit

Cross Reactivity

Human

Target

TREX1

Clonality

Recombinant

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human TREX1

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11277

Isotype

IgG

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