CD112 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.
Synonyms
HVEB; PRR2; CD112; PVRR2.
Gene ID
5819
Swiss Prot
Q92692
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
CD112
Clonality
Recombinant
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human Nectin 2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5819
Isotype
IgG
Curated Selection
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